5-Amino-1MQ — Small-molecule NNMT Inhibitor Research
Small-molecule NNMT inhibitor · Preclinical research
5-Amino-1MQ
Investigated in cell-culture and animal models as an inhibitor of nicotinamide N-methyltransferase (NNMT). Published human efficacy and safety data are not established.
Whole-body metabolic context
Research into NNMT inhibition begins at the systemic level, examining how adipose tissue distribution and metabolic rate respond in animal models. No established human efficacy data exists at this time.
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme overexpressed in obese adipose tissue. It is not a peptide. Published evidence is primarily from cell-culture and rodent studies; established human efficacy, optimal dosing, and long-term safety data are not available.
In preclinical models, NNMT inhibition has been associated with increased intracellular NAD⁺ levels in adipocytes, reduced fat-cell size, and downstream activation of SIRT1 and AMPK pathways. These findings have not been replicated in controlled human trials.
For research use only — not for human consumption.
5 mg lyophilized vial
$60.00
In stock
For research use only — not for human consumption.