HGH Fragment 176-191
Isolated lipolytic fragment of HGH for targeted fat loss research.
250 mcg twice daily
Key Benefits
12.5× more potent than full HGH for fat breakdown
clean metabolic profile without growth-promoting side effects
demonstrated in preclinical obesity models
does not affect glucose metabolism
Recommended Injection Sites
Optimal injection locations for HGH Fragment 176-191 based on its route (Subcutaneous injection) and pharmacokinetic profile.
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Preferred for metabolic peptides.
Good alternative.
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- IV administration
- Intramuscular injection
Active Signaling Pathway
How long will one vial last?
Based on standard research protocols, here's exactly what to expect from a single 2mg vial — and when to plan your next order.
Actual duration may vary based on your specific protocol. Always consult your research guidelines for precise dosing schedules.
Scientific Background
Mechanism of Action
The 176-191 fragment binds beta-3 adrenergic receptors on adipocytes, activating hormone-sensitive lipase (HSL) to break down stored triglycerides. Unlike full HGH, it does not bind the GH receptor or activate IGF-1 signaling, giving it a clean metabolic profile.
Clinical Context
HGH Fragment 176-191 is closely related to AOD-9604 (which has additional modifications). Both represent the lipolytic domain of HGH isolated for targeted metabolic research.
Research Highlights
- Shown to be 12.5× more potent than full HGH for fat loss in preclinical studies
- Does not affect blood glucose, insulin sensitivity, or IGF-1 levels
- Demonstrated significant reduction in abdominal fat in obese rodent models
- Phase 2 clinical trials showed favorable safety profile in human subjects
Storage & Reconstitution
Store at -20°C. Reconstitute with 1 mL bacteriostatic water → 2 mg/mL. Stable 4 weeks at 2–8°C.
Best administered fasted for maximum lipolytic effect. Typical cycle: 8–12 weeks.